Colistin Sulfate

Category:

Molecular Formula: C52H98N16O13
CAS Number: 1264-72-8
Specification: USP/BP/EP
Appearance: White to off-white powder

 

Colistin, also known as polymyxin E, is an antibiotic produced by certain strains of the bacteria Paenibacillus polymyxa. Colistin is a mixture of the cyclic polypeptides colistin A and B and belongs to the class of polypeptide antibiotics known as polymyxins. Colistin is effective against most Gram-negative bacilli. Colistin has also been used recently to treat ventilator-associated pneumonia (VAP) and bacteremia caused by MDR bacteria, such as P. aeruginosa, K. pneumoniae and A. baumannii. Alhough the use of colistin is considered to be effective, other antibiotics are often used in combination with colistin.

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