Decoquinate

Molecular Formula: C24H35NO5
CAS Number: 18507-89-6
Appearance: Cream To Buff Fine Powder

Decoquinate is a 4-hydroxyquinolone coccidiostat that inhibits electron transport in protozoal mitochondria and interferes with sporozoite development. It likely has a similar mechanism of action to atovaquone, because resistance to atovaquone can result in cross-resistance to decoquinate. Although developed as a food additive for use in production animals, decoquinate can be used successfully and without adverse effects to prevent relapses in dogs that are chronically infected with Hepatozoon americanum. Decoquinate also appeared to be effective for treatment of Sarcocystis spp. myositis in a dog.